Global dental industry has undergone a drastic transformation over the last decade. Teeth are among the most important part of human beings, which helps in performing various activities ranging from feeding to articulation to that of esthetics, loss of which could led to physical and psychological issues. As such, many advancements have been made in the past to cater to growing dental issues among patients, including denatures and dental implants.
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Though major advancements has been made in the field of dentistry, emotional connect with natural teeth and high attributes of natural teeth has led to attention on development of biologically engineered teeth (tooth regeneration). Various new companies have emerged at the global level to address and capitalize on highly lucrative opportunities in the market. Industry leaders and universities across regions are actively working towards developing novel products and solutions to develop new teeth. Once commercialized, tooth regeneration market is expected to capture much of the dental implants market.
Research are carried out by various universities and companies to understand the feasibility of stem cell based regenerative medicines – tooth regeneration. While stem cell is the prominent technology in research for tooth regeneration, some institutions are also leveraging laser, drug and gel as mediums to regenerate teeth. For instance, Wyss Institute at Harvard University is engaged in research related to tooth regeneration using lasers. Tooth generated using stem cells are currently under research across the globe. Dental pulp stem cells, stem cells from human exfoliated deciduous teeth (SHEDs), periodontal ligament stem cells (PDLSCs), stem cells from apical papilla (SCAPs), dental follicle progenitor cells (DFPCs) are key stem cells on which research are carried out.
Tooth regeneration market industry players are expected to witness increase exponential increase in their revenue. Early entrants are expected to gain significantly from first mover advantage. The market is expected to be primarily driven by high tooth loss prevalence coupled with focus of major players on product innovation and need for aesthetic look among target population. Dental cavities and issues are treated with conventional invasive methods such as dental implants and root canal. Development of non-invasive methods such as tooth regeneration would be a major breakthrough innovation and would replace dental implants. A 2009 nationwide survey by the Nova Southeastern University in the U.S. revealed that around 96% of dentists expect stem cell regeneration to dominate the future of dentistry industry.
With changing dental industry landscape, companies are emphasizing on product innovation in order to sustain and expand their business reach worldwide. Tooth regeneration is one such disruptive technology wherein early entrants are expected to capture major share of the dental market. Moreover, commercialization of tooth regeneration will lead to slowdown in the dental implant and equipment landscape. As such, tooth regeneration industry will dominate the whole dental market. Though the tooth regeneration holds immense potential to generate high ROI and at same time benefit society, high R&D cost and stringent regulations are key challenges being faced by the industry players.
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Key companies covered as a part of this study include Institut Straumann Ag, DENTSPLY Implants, Unilever and Datum Dental.
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