Cancer biomarkers are biological molecule produced either by tumor cells or by human tissues in response to cancer, which then measured and evaluated as an indicator of cancerous processes within the body. Cancer biomarkers are extensively used in detection and management of patients with cancer. In patients, who undergone curative surgery for cancer, biomarkers are used in follow-up surveillance and for early detection of possible recurrent disease. Moreover, continuous advancements in cancer diagnosis includes use of molecular biomarkers as part of routine diagnostic tests. Molecular alterations used for cancer diagnosis involves application of DNA, RNA, microRNAs, and proteins. Governments of various countries are focusing on investing in prevention and early intervention of cancer, to reduce emotional and physical impact of cancer on patients and their families. Moreover, national healthcare departments are involved in continuous development in cancer research and treatment. Increasing incidence of cancer is expected to lead to innovation and development in the area of cancer diagnosis with biomarker. For instance, according to the 2015 data findings, U.K. Department of Health & Social Care invests US$ 7.5 billion on cancer related treatment and services, annually.
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The global cancer biomarkers market was valued at US$ 11.6 billion in 2017 and is expected to witness a CAGR of 14.2% over the forecast period (2017–2025).
Growing Research and Development Funding from Various Government and Private Organizations is a Factor Driving Growth of the Cancer Biomarkers Market
Various government and private organizations are focusing on increasing investment in R&D for cancer biomarkers. This is owing to increasing incidence and prevalence of cancer, globally. For instance, in June 2018, Cancer Research UK, proposed funding of US$ 140,922 per year, through biomarker project for biomarker assay development, validation, and qualification for use in cancer clinical diagnosis. Furthermore, in March 2016, the National Cancer Institute (NCI) invested US$ 5.5 million in 2016, for setting up of laboratories to conduct research on biomarkers and biomarker assays for cancers of the breast, prostate, lung, and genitourinary organs, and also to those cancers, which have high incidence rate. In April 2016, University of Auckland received a US$ 10 million grant to conduct research in cancer biomarkers, from Auckland entrepreneur, Mr Liangren Li and his family. The grant was allocated for initiating the PROSPER (Profiling of Oncology Patients as part of Clinical care and Research) project. In 2016, National Cancer Institute (NCI) invested US$ 3.9 billion for cancer research activities, which accounts for 70.8% of overall NCI 2016 budget. It invested around US$ 533 million on cancer detection and diagnostic research activities. Moreover, in 2016, NCI allocated 40.4% of its funds for Research Project Grants (RPGs). Furthermore, in 2017, NCI budget increased by US$ 454 million (8.7%) from previous year (2016) for cancer research activities. These increasing research and development (R&D) activities in biomarkers is expected augment growth of global cancer biomarkers market.
The global cancer biomarkers market is projected to witness significant growth over the forecast period, owing to rising incidence and prevalence of various cancer types, including breast cancer, lung cancer, kidney cancer, liver cancer, prostate cancer, and among others. Moreover, other factors impacting growth of cancer biomarkers market includes rising research and development activities in developing cancer biomarker and rising demand for personalized medicine in cancer therapies. For instance, according to the Cancer Atlas: 2017, there were an estimated 14.1 million new cancer cases in 2012. Moreover, India, China and other East and Central Asian countries accounted for nearly half of world’s new cancer cases and deaths, in 2017. Furthermore, according to the same source, by 2025, there will be an estimated 19.3 million new cancer cases and 11.4 million cancer deaths, in emerging economies. However, high cancer treatment cost and unfavorable reimbursement policies for cancer biomarker may hinder the growth of cancer biomarkers market.
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Key companies covered as a part of this study include BioMerieux S.A., Bard1 Life Sciences Limited, Bio-Rad Laboratories, Abbott Laboratories, Becton, Dickinson and Company, Merck & Co., Inc., Qiagen N.V., and Thermo Fisher Scientific Inc.
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